a study deciphers the associated biological disorders ⋅ Inserm, From science to health

If we know the clinical consequences of chronic smoking – premature aging, cardiovascular disease, cancer – the biological pathways involved are not fully described. One team just highlighted several biomarkers altered specifically in smokers, which could help prevent the risks associated with smoking.

Smoking promotes premature tissue aging and increases the risk of developing cancer. It also degrades cardiovascular health by promoting increased vascular stiffness and thickening of the wall of key blood vessels such as the carotid artery. If the consequences of tobacco use are well known, the biological mechanisms at work are not yet well described. A team from Lorraine has also been looking for biomarkers in the blood that may link smoking to its clinical repercussions.

For this, Tripti Rastogi * and colleagues used data from the Stanislas cohort